Oprah Winfrey and Gayle King are reported fighting over 50 Cent as the TV queen is reportedly unhappy with her friendship as she had a beef with the rapper.

Gayle invited 50 - who they have nicknamed 'Fitty' - onto her talk show last month and the two even joked that they were a couple. While Oprah went along with the joke, it seems that she was secretly fuming at her best friend for getting pally with him.

"She's livid that the woman she expects absolute loyalty from is getting chummy with a bad boy who publicly mocks her," a source told the National Enquirer. "Oprah has been a longtime opponent of rap music that is violent and demeaning to women, and she considers Fitty to be one of the worst offenders."

"Oprah hates him! She thinks his lyrics are degrading to all women, and Oprah can't for the life of her figure out why Gayle would fall for him. After everything Fitty has said about Oprah over the years, she doesn't understand how Gayle could possibly be interested in being friends with him, let alone trying to pursue a relationship."

The source also claims that oprah has labelled Gayle a cougar, adding: "Oprah told Gayle she's making a fool of herself by chasing around a man young enough to be her son."

Should Oprah leave Gayle to it or should Gayle stop acting like a "cougar?"

50 Cent signs copies of his 'Playground' book in NYC...